Journal: Journal of Clinical Medicine
Article Title: Analysis of IL-17A, IL-17F, and miR-146a-5p Prior to Transplantation and Their Role in Kidney Transplant Recipients
doi: 10.3390/jcm13102920
Figure Lengend Snippet: Relationships between IL-17A/IL-17F serum levels, gene polymorphisms, and miR-146a-5p expression. ( a ) The IL-17F rs763780 G allele is associated with an increased IL-17 concentration in the serum of patients; ( b ) a higher expression of miR-146a-5p is associated with an increased IL-17A serum concentration. No significant association was observed between the IL-17A variant and the IL-17A serum level or the IL-17A concentration and miR-146a-5p expression (not shown). Statistical analysis was performed using a Mann–Whitney test ( a ) and an unpaired t -test ( b ).
Article Snippet: A sandwich enzyme-linked immunosorbent assay (ELISA) was used to assess IL-17A (IL-17 Quantikine ELISA Kit (D1700), R&D Systems, Minneapolis, MN, USA) and IL-17F (Human IL-17F DuoSet ELISA (DY1335B), R&D Systems, USA) concentrations in the serum samples of 77 patients.
Techniques: Expressing, Concentration Assay, Variant Assay, MANN-WHITNEY